THE SCIENCE OF METABOLISM AND HEALTHY AGING
September 21, 2020
Harvard BBS Graduate Student Talia Hart receives a perfect "10" score on her NIH R36 proposal to study mechanisms of healthy aging. Congratulations Talia!
ABOUT THE SOUKAS LAB
We use genetic approaches from human to mouse to worm
to uncover the mysteries of aging and aging-associated diseases
such as diabetes, obesity, and cancer.
Our work informs the next generation of therapies aimed at promoting health in humans.
The Soukas Lab is located within the Center for Genomic Medicine at the Massachusetts General Hospital and Harvard Medical School in Boston, Massachusetts, USA. We are centrally situated in downtown Boston in the state-of-the-art Simches Research Building, a multidisciplinary research center with investigators in Molecular Biology, Stem Cell and Regenerative Medicine, Cancer Biology, Systems Biology, Cardiovascular Research, and Genomics.
The lab is also an Associate Member Lab of the
Broad Institute of Harvard and MIT and has access to all the technology and capabilities the Broad has to offer.
To see what the lab is up to scientifically, see OUR SCIENCE
Metabolic Phenotyping Core
Creation of Medically Relevant Models via Genomic Targeting in a Variety of Cell Types
siRNA, shRNA, CRISPR
Primary Hepatocytes and Adipocytes
iPS Cells and iPS derived Hepatocyte-Like Cells and Adipocyte-Like Cells
A Panel of Sophisticated Metabolic Phenotyping Assays Can be Carried Out on Primary Human, Mouse, or Model-Derived Samples
Metabolomics and Lipidomics
Insulin Signaling Assays
Hepatocyte Glucose Output
MRI Body Composition Analysis (Mice)
Energy Expenditure in mice (Sable Promethion)
CONTACT THE SOUKAS LAB
Massachusetts General Hospital
Harvard Medical School
Simches Research Building
185 Cambridge Street
Boston, MA 02114